Patent: 6,572,863
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Summary for Patent: 6,572,863
| Title: | Constitutive expression of non-infectious HIV-like particles |
| Abstract: | Non-infectious, non-replicating immunogenic HIV-like particles are produced by stable long-term constitutive expression in mammalian cells by eliminating elements toxic to the mammalian cells. An expression vector contains a nucleic acid molecule comprising a modified HIV genome devoid of long terminal repeats and wherein Tat and vpr sequences are functionally disabled and a constitutive promoter operatively connected to the modified HIV genome for constitutive expression of the modified genome to produce the HIV-like particles. |
| Inventor(s): | Rovinski; Benjamin (Thornhill, CA), Yao; Fei-Long (Toronto, CA), Cao; Shi Xian (Etobicoke, CA) |
| Assignee: | Aventis Pasteur Limited (Toronto, CA) |
| Application Number: | 09/555,834 |
| Patent Claims: | see list of patent claims |
Details for Patent 6,572,863
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2017-12-16 |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2017-12-16 | |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2017-12-16 | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
