Patent: 6,387,711
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Summary for Patent: 6,387,711
| Title: | Liquid intact parathyroid hormone (PTH) standards |
| Abstract: | A solution of a non-reconstituted hormone and a preservative having a useful shelf life of at least six months, and, in some circumstances, at least a year. A series of solution of varying levels of the non-reconstituted hormone may be in a test kit and used in a process to determine the level of the hormone in a patient sample. In an aspect of the invention, the hormone is parathyroid hormone. The preservatives may be polyvinyl alcohol, a dissolved EDTA salt, or dissolved sodium molybdate. The hormone may be in an aqueous or a buffered matrix containing very little protein and substantial amounts of TX100 to reduce non-specific binding. The solution is incubated with a solid phase coated with an anti-hormone antibody and a labeled hormone antibody. The solid phase is read using a suitable device for measuring the labeled hormone antibody. An example of a labeled hormone antibody is an acridinium labeled hormone antibody that is read using a light reading device. |
| Inventor(s): | Sundaram; Lata (Laguna Niguel, CA), Hoang; Ann (Lake Forest, CA), Shimizu; Stan (Trabuco Canyon, CA) |
| Assignee: | Quest Diagnostics Investments Incorporated (Wilmington, DE) |
| Application Number: | 09/637,649 |
| Patent Claims: | see list of patent claims |
Details for Patent 6,387,711
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Nps Pharmaceuticals, Inc. | NATPARA | parathyroid hormone | For Injection | 125511 | 01/23/2015 | ⤷ Try a Trial | 2039-03-29 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
