Patent: 6,265,204
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Summary for Patent: 6,265,204
Title: | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi |
Abstract: | The invention includes novel fusion nucleic acids encoding fusion polypeptides which when expressed in a filamentous fungus result in the expression of fusion polypeptides. The fusion nucleic acids comprise four nucleic acids which encode a fusion polypeptide comprising first, second, third and fourth amino acid sequences. The first nucleic acid encodes a signal polypeptide functional as a secretory sequence in a first filamentous fungus. The second nucleic acid encodes a secreted polypeptide or functional portion thereof which is normally secreted from the same filamentous fungus or a second filamentous fungus. The third nucleic acid encodes a cleavable linker while the fourth nucleic acid comprises at least two nucleic acids encoding desired polypeptides. |
Inventor(s): | Ward; Michael (San Francisco, CA), Power; Scott D. (San Bruno, CA) |
Assignee: | Genencor International, Inc. (Rochester, NY) |
Application Number: | 08/785,668 |
Patent Claims: | see list of patent claims |
Details for Patent 6,265,204
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Try a Trial | 2039-02-26 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |