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Last Updated: April 25, 2024

Patent: 5,981,214


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Summary for Patent: 5,981,214
Title: Production of proteins using homologous recombination
Abstract:Methods and compositions are provided for expression of mammalian genes in culture. An amplifiable gene is introduced by homologous recombination in juxtaposition to a target gene, the resulting combination of amplifiable gene and target gene transferred to a convenient host and the target gene amplified by means of the amplifiable gene. The resulting expression host may then be grown in culture with enhanced expression of the target gene.
Inventor(s): Skoultchi; Arthur I. (Larchmont, NY)
Assignee: Cell Genesys, Inc. (Foster City, CA)
Application Number:08/467,244
Patent Claims:see list of patent claims

Details for Patent 5,981,214

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2016-11-09
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2016-11-09
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2016-11-09
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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