Patent: 5,914,265
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Summary for Patent: 5,914,265
Title: | Keratin K1 expression vectors and methods of use |
Abstract: | A keratin K1 vector for expression of a nucleic acid sequence in an epidermal cell. The vector includes a 5\' flanking region which includes necessary sequences for expression of a nucleic acid cassette, a keratin K1 3\' flanking region which regulates expression of a nucleic acid sequence, predominantly in the epidermis, and a linker which connects the 5\' flanking region to a nucleic acid. The linker has a position for inserting a nucleic acid cassette. The linker does not contain the coding sequence of a gene that the linker is naturally associated with. That is, the linker is not the normal gene associated with the 5\' and 3\' regions. |
Inventor(s): | Roop; Dennis R. (Houston, TX), Rothnagel; Joseph A. (Houston, TX), Greenhalgh; David A. (Houston, TX), Yuspa; Stuart H. (Bethesda, MD) |
Assignee: | Baylor College of Medicine (Houston, TX) The United States of America as represented by the Department of Health (Washington, DC) |
Application Number: | 08/147,777 |
Patent Claims: | see list of patent claims |
Details for Patent 5,914,265
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2016-06-22 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2016-06-22 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2016-06-22 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |