Patent: 5,856,442
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Summary for Patent: 5,856,442
Title: | Transcripts of the MHC class I HLA-G gene and their applications |
Abstract: | Transcripts of the major histocompatibility complex (MHC) Class I HLA-G gene which are present in foetal trophoblasts and/or in adult circulating mono-nuclear cells, as well as methods of using these. Either the said transcripts comprise, in succession in the 5\' to 3\' direction: a fragment encoding the signal peptide (exon 1), a fragment encoding the .alpha.1 domain (exon 2), a fragment encoding the .alpha.2 domain (exon 3), a fragment encoding the transmembrane TM domain (exon 5), a fragment encoding the cytoplasmic domain (exon 6) and the 3\' untranslated fragment (exon 8), which sequence is designated HLA-G4, or the said transcripts comprise intron 4. |
Inventor(s): | Carosella; Edgardo Delfino (Paris, FR), Moreau; Philippe (Viry-Chatillon, FR), Gluckman; Eliane (Paris, FR), Kirszenbaum; Marek (Orsay, FR) |
Assignee: | Commissariat a l\'Energie Atomique (Paris, FR) |
Application Number: | 08/406,057 |
Patent Claims: | see list of patent claims |
Details for Patent 5,856,442
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2016-01-05 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2016-01-05 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2016-01-05 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |