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Last Updated: April 23, 2024

Patent: 5,717,084

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Summary for Patent: 5,717,084

Title:	Chimaeric gene coding for a transit peptide and a heterologous peptide
Abstract:	A chimaeric DNA sequence comprising: a) a nucleic acid sequence coding for a chimaeric protein or polypeptide comprising in sequence: 1) a transit peptide of a cytoplasmatic precursor of a chloroplast protein or polypeptide of a plant species, and, 2) a protein or polypeptide of interest which is different from a mature chloroplast protein or polypeptide contained in a natural cytoplasmatic precursor thereof, and, b) a promoter upstream of the nucleic acid sequence recognized by polymerases endogenous to a plant, whereby the chimaeric DNA sequence can be expressed in cells of the plant under the control of the promoter and the protein or polypeptide of interest can be translocated in the chloroplasts of the cells of the plant.
Inventor(s):	Herrera-Estrella; Luis (Ghent, BE), Van Den Broeck; Guido (Ghent, BE), Van Montagu; Marc (Brussels, BE), Schreier; Peter (Cologne, DE), Schell; Jeff (Cologne, DE), Bohnert; Hans J. (Tucson, AZ), Cash more; Anthony R. (Woodside, NY), Timko; Michael P. (New York, NY), Kausch; Albert P. (Durham, NH)
Assignee:	Plant Genetic Systems, N.V. (Brussels, BE) Bayer A.G. (Leverkusen, DE)
Application Number:	08/470,719
Patent Claims:	see list of patent claims

Details for Patent 5,717,084

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2015-02-10
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2015-02-10
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2015-02-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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