Patent: 5,714,313
✉ Email this page to a colleague
Summary for Patent: 5,714,313
Title: | Simple method for detecting inhibitors of retroviral replication |
Abstract: | The present invention relates, in general, to a DNA segment. In particular, the present invention relates to a DNA segment comprising a selectable marker gene, a DNA segment comprising a selectable marker gene inserted into a retrotransposon, cells containing these DNA segments, and methods of using these DNA segments and cells. The present invention further relates to a vector comprising a selectable marker gene inserted into a retrotransposon, wherein the retrotransposon comprises a retroviral reverse transcriptase/RNase H gene domain and wherein the selectable marker gene contains an intron inserted into a coding sequence of the marker gene and the intron is in antisense orientation relative to transcription of the marker gene and in sense orientation relative to transcription of the retrotransposon. |
Inventor(s): | Garfinkel; David J. (Frederick, MD), Nissley; Dwight V. (Frederick, MD), Curcio; Joan M. (Albany, NY), Strathern; Jeffrey N. (Frederick, MD) |
Assignee: | United States of America as represented by the Department of Health and (Washington, DC) |
Application Number: | 08/449,207 |
Patent Claims: | see list of patent claims |
Details for Patent 5,714,313
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2015-02-03 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2015-02-03 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2015-02-03 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |