Patent: 5,695,955
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Summary for Patent: 5,695,955
| Title: | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| Abstract: | Synthetic polypeptide analogs of parathyroid hormone PTH, parathyroid hormone related peptide PTHrp, and of the physiologically active truncated homologs and analogs of PTH and PTHrp, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, these residues (22-31) selected from hydrophilic amino acids (Haa) and lipophilic amino acids (Laa) ordered in the sequence: and their pharmaceutically acceptable salts are useful for the prophylaxis and treatment of ostoporosis in mammals. Processes for the production of the polypeptides via solid phase and recombinant methods are provided. |
| Inventor(s): | Krstenansky; John L. (Palo Alto, CA), Nestor, Jr.; John J. (Cupertino, CA), Ho; Teresa H. (Los Altos, CA), Vickery; Brian H. (Mountain View, CA), Bach; Chinh T. (San Jose, CA) |
| Assignee: | Syntex (U.S.A.) Inc. (Palo Alto, CA) |
| Application Number: | 08/448,070 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,695,955
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Nps Pharmaceuticals, Inc. | NATPARA | parathyroid hormone | For Injection | 125511 | 01/23/2015 | ⤷ Try a Trial | 2014-12-09 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
