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Last Updated: September 22, 2021

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Patent: 5,602,006

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Summary for Patent: 5,602,006
Title: Heteropolymeric protein production methods
Abstract:Cultured mammalian cell transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
Inventor(s): Kelton; Christie A. (Hopkinton, MA), Nugent; Noreen P. (Framingham, MA), Chappel; Scott C. (Boston, MA)
Assignee: Genzyme Corporation (Cambridge, MA)
Application Number:08/455,396
Patent Claims:see list of patent claims

Details for Patent 5,602,006

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 004 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 006 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 007 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 009 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 010 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 011 1975-06-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 RX search
Bel Mar CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017054 001 1974-03-26 ⤷  Free Forever Trial Genzyme Corporation (Cambridge, MA) 2014-02-11 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 5,602,006

Country Patent Number Estimated Expiration
Austria 159544 ⤷  Free Forever Trial
Austria 251216 ⤷  Free Forever Trial
Canada 2018676 ⤷  Free Forever Trial
Germany 69031611 ⤷  Free Forever Trial
Germany 69034104 ⤷  Free Forever Trial
Denmark 0735139 ⤷  Free Forever Trial
European Patent Office 0404546 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration

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