Patent: 4,845,075
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Summary for Patent: 4,845,075
Title: | Biologically active B-chain homodimers |
Abstract: | Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the B-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the B-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the B-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed. |
Inventor(s): | Murray; Mark J. (Seattle, WA), Kelly; James D. (Seattle, WA) |
Assignee: | ZymoGenetics, Inc. (Seattle, WA) |
Application Number: | 06/942,161 |
Patent Claims: | see list of patent claims |
Details for Patent 4,845,075
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | ZOSTAVAX | zoster vaccine live | For Injection | 125123 | 05/25/2006 | ⤷ Try a Trial | 2006-07-04 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |