Patent: 4,263,293
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Summary for Patent: 4,263,293
Title: | Heterocyclic containing amides as inhibitors of mammalian collagenase |
Abstract: | Mammalian collagenase is inhibited by compounds having the formula ##STR1## wherein R.sub.1 is hydrogen, alkanoyl of 2 to 10 carbon atoms or arylcarbonyl; R.sub.2 is 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl, 1-piperazinyl, or 4-alkyl-1-piperazinyl; R.sub.3 is alkyl of 3 to 8 carbon atoms, cycloalkyl, aryl, or arylalkyl; and n is an integer of 1 to 20. |
Inventor(s): | Sundeen; Joseph E. (Yardley, PA), Dejneka; Tamara (Skillman, NJ) |
Assignee: | E. R. Squibb & Sons, Inc. (Princeton, NJ) |
Application Number: | 06/154,748 |
Patent Claims: | see list of patent claims |
Details for Patent 4,263,293
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Try a Trial | 2039-03-29 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |