You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: March 29, 2024

Patent: 4,098,645


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 4,098,645
Title: Immobilization of proteins with polyurethane polymers
Abstract:A protein which can be an enzyme is immobilized by: (a) admixing the protein and an isocyanate-capped liquid polyurethane prepolymer in the absence of water to form a resulting mixture (an intermediate product); and (b) forming the intermediate product by reacting it with water to form a polyurethane foam comprising the immobilized enzyme. When certain proteins in sufficient amount are mixed with the prepolymer in the absence of water the resultant protein prepolymer mixture will solidify to produce a solid non-foamed product containing a protein immobilized therein. Initially mixing the protein and prepolymer in the absence of water results in immobilization of a substantially greater amount of protein than when water is present.
Inventor(s): Hartdegen; Frank Joseph (Columbia, MD), Swann; Wayne Elliott (Pasadena, MD)
Assignee: W. R. Grace & Co. (New York, NY)
Application Number:05/743,035
Patent Claims:see list of patent claims

Details for Patent 4,098,645

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 01/10/1978 ⤷  Try a Trial 1996-02-24
Csl Behring Ag CARIMUNE, CARIMUNE NF, PANGLOBULIN, SANDOGLOBULIN immune globulin intravenous (human) For Injection 102367 07/27/2000 ⤷  Try a Trial 1996-02-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 07/26/2007 ⤷  Try a Trial 1996-02-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 10/02/2009 ⤷  Try a Trial 1996-02-24
Csl Behring Ag PRIVIGEN immune globulin intravenous (human), 10% liquid Injection 125201 02/07/2013 ⤷  Try a Trial 1996-02-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.