Patent: 4,028,187
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Summary for Patent: 4,028,187
Title: | Method of obtaining urokinase |
Abstract: | A method of obtaining urokinase directly from human urine comprising contacting human urine with an acrylonitrile polymer of a unique porous structure formed at the time of polymerization for formation of the polymer and having a porosity of not less than 10% and a specific surface area of 5 m.sup.2 /g. and subsequently eluting the urokinase adsorbed on the polymer. The acrylonitrile polymer employed in the method of the present invention has an excellent adsorption activity to urokinase and therefore, with use of an extremely small amount of the adsorbent, the satisfactory results can be obtained. Moreover, the porous polymer of the present method can also be utilized for purification of low purity crude urokinase obtained by the prior art methods. |
Inventor(s): | Tsutomu; Abe (Fuji, JA), Yasuo; Hashino (Fuji, JA), Hidehiko; Kobayashi (Fuji, JA) |
Assignee: | Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JA) |
Application Number: | 05/701,930 |
Patent Claims: | see list of patent claims |
Details for Patent 4,028,187
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Microbix Biosystems Inc. | KINLYTIC | urokinase | For Injection | 021846 | 01/16/1978 | ⤷ Try a Trial | 1995-07-04 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |