Patent: 10,653,645
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Summary for Patent: 10,653,645
Title: | Method for enhancing folding and transport of misfolded glucocerebrosidase |
Abstract: | Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof. |
Inventor(s): | Mahuran; Don J. (Toronto, CA), Tropak; Michael B. (Toronto, CA), Buttner; Justin D. (Rosehill, AU), Blanchard; Jan E. (St. Catherines, CA), Brown; Eric D. (Oakville, CA) |
Assignee: | The Hospital for Sick Children (Toronto, Ontario, CA) McMaster University (Hamilton, Ontario, CA) |
Application Number: | 16/014,739 |
Patent Claims: | see list of patent claims |
Details for Patent 10,653,645
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Genzyme Corporation | CEREZYME | imiglucerase | For Injection | 020367 | 05/23/1994 | ⤷ Try a Trial | 2027-09-17 |
Genzyme Corporation | CEREZYME | imiglucerase | For Injection | 020367 | 09/22/1999 | ⤷ Try a Trial | 2027-09-17 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |