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Last Updated: March 28, 2024

Patent: 10,653,645


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Summary for Patent: 10,653,645
Title:Method for enhancing folding and transport of misfolded glucocerebrosidase
Abstract: Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof.
Inventor(s): Mahuran; Don J. (Toronto, CA), Tropak; Michael B. (Toronto, CA), Buttner; Justin D. (Rosehill, AU), Blanchard; Jan E. (St. Catherines, CA), Brown; Eric D. (Oakville, CA)
Assignee: The Hospital for Sick Children (Toronto, Ontario, CA) McMaster University (Hamilton, Ontario, CA)
Application Number:16/014,739
Patent Claims:see list of patent claims

Details for Patent 10,653,645

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 05/23/1994 ⤷  Try a Trial 2027-09-17
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 09/22/1999 ⤷  Try a Trial 2027-09-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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