Patent: 10,206,882
✉ Email this page to a colleague
Summary for Patent: 10,206,882
Title: | Stable digestive enzyme compositions |
Abstract: | Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing. |
Inventor(s): | Ortenzi; Giovanni (Monza, IT), Marconi; Marco (Cinisello Balsamo, IT), Mapelli; Luigi (Milan, IT) |
Assignee: | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (Dublin, IE) |
Application Number: | 14/043,923 |
Patent Claims: | see list of patent claims |
Details for Patent 10,206,882
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Organon Usa Inc., A Subsidiary Of Merck & Co., Inc. | COTAZYM | pancrelipase | Capsule, Delayed Release | 020580 | 12/09/1996 | ⤷ Try a Trial | 2027-02-20 |
Abbvie Inc. | CREON | pancrelipase | Capsule, Delayed Release | 020725 | 04/30/2009 | ⤷ Try a Trial | 2027-02-20 |
Abbvie Inc. | CREON | pancrelipase | Capsule, Delayed Release | 020725 | 06/10/2011 | ⤷ Try a Trial | 2027-02-20 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |