Patent: 10,183,977
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Summary for Patent: 10,183,977
Title: | Stabilized STAT3 decoy oligonucleotides and uses therefor |
Abstract: | The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer. |
Inventor(s): | Grandis; Jennifer R. (Pittsburgh, PA), Johnson; Daniel E. (Glenshaw, PA), Ly; Danith (Pittsburgh, PA) |
Assignee: | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, PA) CARNEGIE MELLON UNIVERSITY (Pittsburgh, PA) |
Application Number: | 15/611,298 |
Patent Claims: | see list of patent claims |
Details for Patent 10,183,977
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Eli Lilly And Company | ERBITUX | cetuximab | Injection | 125084 | 02/12/2004 | ⤷ Try a Trial | 2029-12-17 |
Eli Lilly And Company | ERBITUX | cetuximab | Injection | 125084 | 03/28/2007 | ⤷ Try a Trial | 2029-12-17 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |