Patent: 10,143,677
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Summary for Patent: 10,143,677
| Title: | Taxane analogs for the treatment of brain cancer |
| Abstract: | Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer. |
| Inventor(s): | McChesney; James D. (Etta, MS), Tapolsky; Gilles H. (Louisville, KY), Emerson; David L. (Longmont, CO), Marshall; John (Washington, DC), Kurman; Michael (Upper Saddle River, NJ), Modiano; Manuel (Tuscon, AZ) |
| Assignee: | TAPESTRY PHARMACEUTICALS, INC. (Atlanta, GA) |
| Application Number: | 15/483,551 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,143,677
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Genentech, Inc. | AVASTIN | bevacizumab | Injection | 125085 | 02/26/2004 | ⤷ Try a Trial | 2027-02-28 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
