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Last Updated: April 25, 2024

Patent: RE42704

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Summary for Patent: RE42704

Title:	Production of fibrinogen in transgenic animals
Abstract:	Materials and methods for producing fibrinogen in transgenic non-human mammals are disclosed. DNA segments encoding A.alpha., B.beta. and .gamma. chains of fibrinogen are introduced into the germ line of a non-human mammal, and the mammal or its female progeny produces milk containing fibrinogen expressed from the introduced DNA segments. Non-human mammalian embryos and transgenic non-human mammals carrying DNA segments encoding heterologous fibrinogen polypeptide chains are also disclosed.
Inventor(s):	Prunkard; Donna E. (Seattle, WA), Foster; Donald C. (Lake Forest Park, WA)
Assignee:	Pharming Intellectual Property B.V. (Al Leiden, NL)
Application Number:	09/232,488
Patent Claims:	see list of patent claims

Details for Patent RE42704

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Csl Behring Gmbh	RIASTAP	fibrinogen concentrate (human)	For Injection	125317	01/16/2009	⤷ Try a Trial	2040-01-28
Octapharma Pharmazeutika Produktionsges.m.b.h.	FIBRYGA, FIBRYNA	fibrinogen (human)	For Injection	125612	06/07/2017	⤷ Try a Trial	2040-01-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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