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Last Updated: July 3, 2020

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Patent: RE29980

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Summary for Patent: RE29980
Title: Method of obtaining urokinase
Abstract:A method of obtaining urokinase directly from human urine comprising contacting human urine with an acrylonitrile polymer of a unique porous structure formed at the time of polymerization for formation of the polymer and having a porosity of not less than 10% and a specific surface area of .Iadd.not less than .Iaddend.5 m.sup.2 /g. and subsequently eluting the urokinase adsorbed on the polymer. The acrylonitrile polymer employed in the method of the present invention has an excellent adsorption activity to urokinase and therefore, with use of an extremely small amount of the adsorbent, the satisfactory results can be obtained. Moreover, the porous polymer of the present method can also be utilized for purification of low purity crude urokinase obtained by the prior art methods.
Inventor(s): Abe; Tsutomu (Fuji, JP), Hashino; Yasuo (Fuji, JP), Kobayashi; Hidehiko (Fuji, JP)
Assignee: Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP)
Application Number:05/856,057
Patent Claims:see list of patent claims

Details for Patent RE29980

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1996-05-01 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1996-05-01 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Asahi Kasei Kogyo Kabushiki Kaisha (Osaka, JP) 1996-05-01 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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