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Last Updated: September 27, 2020

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Patent: 9,987,272

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Summary for Patent: 9,987,272
Title:Compound useful for the treatement of degenerative and inflammatory diseases
Abstract: A pyrazolopyridine compound according to Formula I, able to inhibit JAK is disclosed, as well as pharmaceutically acceptable salts, a solvate thereof, solvates of the pharmaceutically acceptable salts and biologically active metabolites thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment or prophylaxis of a variety of conditions in mammals including humans, and particularly, such conditions as may be associated with aberrant JAK activity, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6. ##STR00001##
Inventor(s): Menet; Christel Jeanne Marie (Mechelen, BE), Hodges; Alastair James (Essex, GB), Vater; Huw David (Essex, GB)
Assignee: GALAPAGOS NV (Mechelen, BE)
Application Number:15/005,442
Patent Claims:see list of patent claims

Details for Patent 9,987,272

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial GALAPAGOS NV (Mechelen, BE) 2031-04-28 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial GALAPAGOS NV (Mechelen, BE) 2031-04-28 RX search
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial GALAPAGOS NV (Mechelen, BE) 2031-04-28 RX Orphan search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Start Trial GALAPAGOS NV (Mechelen, BE) 2031-04-28 RX search
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Start Trial GALAPAGOS NV (Mechelen, BE) 2031-04-28 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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