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Generated: July 20, 2019

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Patent: 9,980,947

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Summary for Patent: 9,980,947
Title:Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof
Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: ##STR00001## and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
Inventor(s): Labadie; Sharada (Sunnyvale, CA), Liang; Jun (Los Altos Hills, CA), Ortwine; Daniel Fred (San Ramon, CA), Wang; Xiaojing (Foster City, CA), Zbieg; Jason (South San Francisco, CA), Zhang; Birong (Union City, CA), Goodacre; Simon Charles (Harlow, GB), Ray; Nicholas Charles (Harlow, GB), Li; Jun (Foster City, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:14/972,326
Patent Claims:see list of patent claims

Details for Patent 9,980,947

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genentech PERJETA pertuzumab VIAL; SINGLE-USE 125409 001 2012-06-08 ➤ Try a Free Trial Genentech, Inc. (South San Francisco, CA) ➤ Try a Free Trial RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ➤ Try a Free Trial Genentech, Inc. (South San Francisco, CA) ➤ Try a Free Trial RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ➤ Try a Free Trial Genentech, Inc. (South San Francisco, CA) ➤ Try a Free Trial RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ➤ Try a Free Trial Genentech, Inc. (South San Francisco, CA) ➤ Try a Free Trial RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Try a Free Trial Genentech, Inc. (South San Francisco, CA) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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