Trophic hormone fusion protein, preparation method and application thereof
Disclosed herein is a gonadotropin fusion protein or a thyroid stimulating hormone fusion protein, a method for preparing the same and use thereof. .beta.-subunit of the gonadotropin or thyroid stimulating hormone is fused to an Fc fragment directly or indirectly through a linker, and .alpha.-subunit binds to the .beta.-subunit via an affinity between the .alpha.-subunit and the .beta.-subunit. The fusion protein has a prolonged half-life and less fluctuating activity.
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