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Last Updated: July 13, 2020

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Patent: 9,969,683

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Summary for Patent: 9,969,683
Title:Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
Abstract: This invention relates to the treatment of breast cancer in a subject, for example a female subject. The breast cancer includes metastatic breast cancer, refractory breast cancer, AR-positive breast cancer, AR-positive refractory breast cancer, AR-positive metastatic breast cancer, AR-positive and ER-positive breast cancer, triple negative breast cancer, advanced breast cancer, breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments, and metastasis in a subject suffering from breast cancer. The method comprises administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound.
Inventor(s): Dalton; James T. (Lakeland, TN), Steiner; Mitchell S. (Germantown, TN), Narayanan; Ramesh (Cordova, TN), Ahn; Sunjoo (Daejeon, KR)
Assignee: GTX, INC. (Memphis, TN)
Application Number:13/953,492
Patent Claims:see list of patent claims

Details for Patent 9,969,683

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial GTX, INC. (Memphis, TN) 2032-07-13 RX search
Genentech KADCYLA ado-trastuzumab emtansine VIAL; SINGLE-USE 125427 002 2013-02-22   Start Trial GTX, INC. (Memphis, TN) 2032-07-13 RX search
Genentech KADCYLA ado-trastuzumab emtansine VIAL; SINGLE-USE 125427 001 2013-02-22   Start Trial GTX, INC. (Memphis, TN) 2032-07-13 RX search
Genentech PERJETA pertuzumab VIAL; SINGLE-USE 125409 001 2012-06-08   Start Trial GTX, INC. (Memphis, TN) 2032-07-13 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial GTX, INC. (Memphis, TN) 2032-07-13 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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