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Last Updated: April 18, 2024

Patent: 9,963,452

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Summary for Patent: 9,963,452

Title:	Methods, compounds, and compositions for inhibition of ROS
Abstract:	The present invention relates to a method using some novel compounds and compositions for the inhibition of ROS tyrosine kinase. In particular, the present invention covers a method to treat abnormal cell growth, such as cancer, with ROS 10 inhibitors and compositions having ROS inhibitors. An illustrative compound of the invention is shown below Formula (I). ##STR00001##
Inventor(s):	Grueneberg; Dorre A. (Newton, MA), Kalid; Ori (Pardes-Hanna, IL), Xian; Jun (Sharon, MA), Rajur; Sharanappa B. (Andover, MA), Kim; Hwa-Ok (Lexington, MA), Neelagiri; Venugopal Rao (Acton, MA), Salgaonkar; Paresh (Medford, MA), Sethumadhavan; Divakaramenon (Waltham, MA), Moon; Chaeho (Burlington, MA), Neelagiri; Madhavi (Acton, MA)
Assignee:	AUGUSTA PHARMACEUTICALS INC. (Newton, MA)
Application Number:	14/775,825
Patent Claims:	see list of patent claims

Details for Patent 9,963,452

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978	⤷ Try a Trial	2033-03-14
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2033-03-14
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2033-03-14
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2033-03-14
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2033-03-14
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	09/25/1998	⤷ Try a Trial	2033-03-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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