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Last Updated: September 27, 2020

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Patent: 9,963,452

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Summary for Patent: 9,963,452
Title:Methods, compounds, and compositions for inhibition of ROS
Abstract: The present invention relates to a method using some novel compounds and compositions for the inhibition of ROS tyrosine kinase. In particular, the present invention covers a method to treat abnormal cell growth, such as cancer, with ROS 10 inhibitors and compositions having ROS inhibitors. An illustrative compound of the invention is shown below Formula (I). ##STR00001##
Inventor(s): Grueneberg; Dorre A. (Newton, MA), Kalid; Ori (Pardes-Hanna, IL), Xian; Jun (Sharon, MA), Rajur; Sharanappa B. (Andover, MA), Kim; Hwa-Ok (Lexington, MA), Neelagiri; Venugopal Rao (Acton, MA), Salgaonkar; Paresh (Medford, MA), Sethumadhavan; Divakaramenon (Waltham, MA), Moon; Chaeho (Burlington, MA), Neelagiri; Madhavi (Acton, MA)
Assignee: AUGUSTA PHARMACEUTICALS INC. (Newton, MA)
Application Number:14/775,825
Patent Claims:see list of patent claims

Details for Patent 9,963,452

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial AUGUSTA PHARMACEUTICALS INC. (Newton, MA) 2033-03-14 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial AUGUSTA PHARMACEUTICALS INC. (Newton, MA) 2033-03-14 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial AUGUSTA PHARMACEUTICALS INC. (Newton, MA) 2033-03-14 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial AUGUSTA PHARMACEUTICALS INC. (Newton, MA) 2033-03-14 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial AUGUSTA PHARMACEUTICALS INC. (Newton, MA) 2033-03-14 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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