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Last Updated: April 19, 2024

Patent: 9,950,042


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Summary for Patent: 9,950,042
Title:Extended length botulinum toxin formulation for human or mammalian use
Abstract: An extended duration pharmaceutical composition including a botulinum neurotoxin, an adhesive agent, and a stabilizing macromolecule is disclosed. The composition effectively has all the properties to cause chemodenervation through a facial muscle, or other muscle, that predecessor botulinum toxin preparations have had as well as agents which create a fibrotic adhesion on the under surface of facial muscles (or other muscles) to the facial bone (or other bones) so that the facial bone tethers the under surface of the facial muscle, thereby causing fibrosis to the underlying fat pad. The composition can be used to treat various disorders. Methods of modifying facial contour for functional or cosmetic purposes in a human patient are disclosed which involve injecting a therapeutically effective amount of the disclosed compositions. A method of quantifying the extended duration of the compositions is also disclosed.
Inventor(s): Borodic; Gary E. (Quincy, MA)
Assignee: REVANCE THERAPEUTICS, INC. (Newark, CA)
Application Number:14/754,268
Patent Claims:see list of patent claims

Details for Patent 9,950,042

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Omrix Biopharmaceuticals Ltd EVITHROM thrombin, topical (human) Solution 125247 08/27/2007 ⤷  Try a Trial 2028-12-04
Omrix Biopharmaceuticals Ltd EVITHROM thrombin, topical (human) For Injection 125247 09/17/2009 ⤷  Try a Trial 2028-12-04
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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