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Generated: July 19, 2019

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Patent: 9,925,310

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Summary for Patent: 9,925,310
Title:Biocompatible and bioabsorbable derivatized chitosan compositions
Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.
Inventor(s): McGrath; Barbara (Portland, OR), McCarthy; Simon (Portland, OR), Kuhn; Sam (Portland, OR), Wold; Alysha (Portland, OR), Stolten; Michael (Portland, OR), Bennett; Amanda (Portland, OR)
Assignee: Tricol Biomedical, Inc. (Portland, OR)
Application Number:15/371,010
Patent Claims:see list of patent claims

Details for Patent 9,925,310

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25 ➤ Sign Up ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,925,310

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2014152796 Nov 20, 2014
World Intellectual Property Organization (WIPO) 2014152796 Sep 25, 2014
United States of America 2014275291 Sep 18, 2014
United States of America 2016266143 Sep 15, 2016
United States of America 2017119934 May 04, 2017
United States of America 2018193531 Jul 12, 2018
United States of America 9547011 Jan 17, 2017
Country Patent Number Publication Date

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