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Generated: July 21, 2019

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Patent: 9,925,260

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Summary for Patent: 9,925,260
Title:Treatment for bone diseases
Abstract: The invention relates to the treatment of bone disorders. In particular, the invention is directed to the use of a dosing holiday to help overcome the resistance to anti-sclerostin antibodies which develops over time when a plurality of doses of antibody are given to a subject. By giving the subject to be treated such a dosing holiday, the subject may subsequently display an increased response to a subsequent dose of the anti-sclerostin antibody. The subject may be given multiple cycles of a batch of at least two doses of anti-sclerostin antibody and a dosing holiday. In some instances, the subject may be monitored to help determine when to give the dosing holiday. Further, the subject may be given a different treatment for the bone disorder during the dosing holiday from the anti-sclerostin antibody.
Inventor(s): Robinson; Martyn Kim (Buckinghamshire, GB)
Assignee: UCB PHARMA S.A. (Slough, GB)
Application Number:13/934,433
Patent Claims:see list of patent claims

Details for Patent 9,925,260

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Amgen XGEVA denosumab INJECTABLE; SUBCUTANEOUS 125320 002 2010-06-01 ➤ Sign Up UCB PHARMA S.A. (Slough, GB) ➤ Sign Up RX Orphan search
Amgen PROLIA denosumab INJECTABLE; SUBCUTANEOUS 125320 001 2010-06-01 ➤ Sign Up UCB PHARMA S.A. (Slough, GB) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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