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Patent: 9,879,067
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Summary for Patent: 9,879,067
| Title: | Stabilized liquid anti-RSV antibody formulations |
| Abstract: | The present invention provides liquid formulations of SYNAGIS.RTM. or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulation exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS.RTM. or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS.RTM. or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulation are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention. |
| Inventor(s): | Oliver; Cynthia N. (North Potomac, MD), Shane; Erica (McLean, VA), Isaacs; Benjamin S. (Andover, MA), Allan; Christian B. (Brookeville, MD), Chang; Stephen T. (Frederick, MD) |
| Assignee: | MedImmune, LLC (Gaithersburg, MD) |
| Application Number: | 15/041,295 |
| Patent Claims: | see list of patent claims |
Details for Patent 9,879,067
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Medimmune | SYNAGIS | palivizumab | VIAL | 103770 | 002 | 1998-06-19 | Start Trial | MedImmune, LLC (Gaithersburg, MD) | 2022-06-14 | RX | search | |
| Medimmune | SYNAGIS | palivizumab | VIAL | 103770 | 001 | 1998-06-19 | Start Trial | MedImmune, LLC (Gaithersburg, MD) | 2022-06-14 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 9,879,067
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 03105894 | Start Trial |
| United States of America | 10604560 | Start Trial |
| United States of America | 2006034827 | Start Trial |
| United States of America | 2007048332 | Start Trial |
| United States of America | 2008286270 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
