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Last Updated: December 1, 2021

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Patent: 9,863,935

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Summary for Patent: 9,863,935
Title:Predictive biomarkers for CTLA-4 blockade therapy and for PD-1 blockade therapy
Abstract: Biomarkers are described for predicting the efficacy, risk of relapse, risk of an immune related adverse event (irAE), or combination thereof for a CTLA-4 blockade treatment, such as ipilimumab, in a subject with melanoma. Biomarkers are also described for predicting the efficacy and clinical benefit for a PD-1 blockade treatment, such as a PD-1 blocking antibody, in a subject with melanoma.
Inventor(s): Weber; Jeffrey S. (Tampa, FL), Wang; Wenshi (Tampa, FL), Yu; Bin (Tampa, FL)
Assignee: H. Lee Moffitt Cancer and Research Institute, Inc. (Tampa, FL)
Application Number:14/399,669
Patent Claims:see list of patent claims

Details for Patent 9,863,935

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bristol-myers Squibb Company YERVOY ipilimumab Injection 125377 2011-03-25 ⤷  Try it Free 2032-05-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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