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Generated: August 24, 2019

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Patent: 9,839,654

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Summary for Patent: 9,839,654
Title:Isolation, expansion and characterization of precursor/stem cells from dental tissues
Abstract: A method for isolating and proliferating at least one type of precursor cell from dental origin from a single donor includes the following isolating the precursor cells from dental origin of a single donor in a sample collection media and preparing a primary stock culture. The primary stock culture is proliferated sequentially to obtain first, second and third sub-cultured stocks with cell counts ranging between 5.times.10.sup.6 cells and 10.times.10.sup.6 cells, 20.times.10.sup.6 cells and 400.times.10.sup.6 cells, 150.times.10.sup.6 and 300.times.10.sup.6 cells respectively. The precursor cells from the third subculture are harvested and cryo-preserved to obtain a precursor cell population for cell transplantation. The dental origin of the precursor cells is from pulp, apical papilla or periodontal ligament. The precursor cell originates from mesenchymal stem cells, ecto-mesenchymal cells, neural stem cells, dental progenitor cells or CD117.sup.+ cells.
Inventor(s): Govindasamy; Vijayendran (Putrajaya, MY), Kathivaloo; Premasangery (Putrajaya, MY)
Assignee: HYGIEIA INNOVATION SDN BHD (Putrajaya, MY)
Application Number:14/831,794
Patent Claims:see list of patent claims

Details for Patent 9,839,654

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up HYGIEIA INNOVATION SDN BHD (Putrajaya, MY) 2034-08-20 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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