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Generated: September 23, 2019

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Patent: 9,835,616

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Summary for Patent: 9,835,616
Title:In vitro method for assessing cytokine storm responses
Abstract: The present disclosure an in vitro method of assaying the stimulation of a cytokine storm response comprising the steps of: a. co-culturing PBMCs and matched differentiated endothelial cells to provide a system representative of human responses in vivo, and b. exposing the co-cultured cell system to a test agent, c. analyzing the system for the presence of one or more cytokines released after exposing the co-culture system to said test agent, and d. optionally evaluating the response to the test agent in comparison to a response to one or more control agents.
Inventor(s): Mitchell; Jane Alison (London, GB)
Assignee: Imperial Innovations Ltd. (London, GB)
Application Number:14/778,729
Patent Claims:see list of patent claims

Details for Patent 9,835,616

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07 ➤ Sign Up Imperial Innovations Ltd. (London, GB) 2033-03-22 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07 ➤ Sign Up Imperial Innovations Ltd. (London, GB) 2033-03-22 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07 ➤ Sign Up Imperial Innovations Ltd. (London, GB) 2033-03-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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