Patent: 9,827,312

Summary for Patent: 9,827,312

Title:	Method for carrying therapeutic substances into cells
Abstract:	The present invention relates to compositions containing nanoparticies and uses of said composition for transferring therapeutically active substances into cells by means of specifically coated nanoparticles. The chemical design of the particles is such that a large amount thereof is absorbed into the cells. No direct bond between nanoparticle and the therapeutically active substance is required for the transfer into the cells. Thanks to said transfer, an increased efficacy of the substance and simultaneously reduced systemic toxicity is achieved, i.e. an increase in the efficacy while the side effects are reduced.
Inventor(s):	Jordan; Andreas (Berlin, DE), Waldoefner; Norbert (Berlin, DE), Scholz; Regina (Berlin, DE)
Assignee:	MAGFORCE AG (Berlin, DE)
Application Number:	14/849,053
Patent Claims:	see list of patent claims

Details for Patent 9,827,312

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978		2025-08-19
Clinigen, Inc.	PROLEUKIN	aldesleukin	For Injection	103293	05/05/1992		2025-08-19
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	02/20/1991		2025-08-19
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	06/28/2000		2025-08-19
Servier Pharmaceuticals Llc	ONCASPAR	pegaspargase	Injection	103411	02/01/1994		2025-08-19
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	09/25/1998		2025-08-19
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	02/10/2017		2025-08-19