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Last Updated: September 28, 2020

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Patent: 9,822,182

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Summary for Patent: 9,822,182
Title:Anti-EPCAM antibodies and methods of use
Abstract: The present disclosure is related to compositions of antibodies and immunoconjugates that potentially lack T-cell epitopes and elicit reduced immune response. The antibody may be an antibody fragment, such as Fab, Fab\', F(ab\')2, scFv, dsFv, ds-scFv, dimers, minibodies, diabodies, bispecific antibody fragments, multimers, and any combination thereof. In a further embodiment, the antibody may bind to an antigen epithelial cell adhesion molecule (EpCAM). In another embodiment, an immunoconjugate may comprise an antibody attached to an effector molecule, wherein the effector molecule may be a radioisotope, an antineoplastic agent, an immunomodulator, a biological response modifier, lectin, a toxin, a chromophore, a fluorophore, a chemiluminescent compound, an enzyme, a metal ion, and any combination thereof.
Inventor(s): Cizeau; Jeannick (Winnipeg, CA), Premsukh; Arjune (Winnipeg, CA), Chooniedass; Shilpa (Winnipeg, CA), MacDonald; Glen (Winnipeg, CA), Entwistle; Joycelyn (Winnipeg, CA)
Assignee: VIVENTIA BIO INC. (Winnipeg, Manitoba, CA)
Application Number:15/026,834
Patent Claims:see list of patent claims

Details for Patent 9,822,182

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial VIVENTIA BIO INC. (Winnipeg, Manitoba, CA) 2033-10-02 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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