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Last Updated: March 28, 2024

Patent: 9,822,158


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Summary for Patent: 9,822,158
Title:Method for preparing crystalline insulin
Abstract: A method for crystallizing insulin or insulin analogs under alkaline conditions and purifying the insulin or insulin analog crystals by filtering through a filter and drying the insulin or insulin analog crystals captured on the filter to produce crystalline insulin or insulin analog crystal compositions is described. In particular aspects, the method may be used to crystalize insulin glargine.
Inventor(s): Ortigosa; Allison D. (Harrisonburg, VA), Perry; William (Longmont, CO), Sleevi; Mark C. (Longmont, CO), Sierra; Luis (Dunellen, NJ)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:15/038,495
Patent Claims:see list of patent claims

Details for Patent 9,822,158

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Sanofi-aventis U.s. Llc LANTUS insulin glargine Injection 021081 04/20/2000 ⤷  Try a Trial 2033-12-04
Sanofi-aventis U.s. Llc LANTUS insulin glargine Injection 021081 04/25/2007 ⤷  Try a Trial 2033-12-04
Eli Lilly And Company BASAGLAR insulin glargine Injection 205692 12/16/2015 ⤷  Try a Trial 2033-12-04
Eli Lilly And Company BASAGLAR insulin glargine Injection 205692 11/15/2019 ⤷  Try a Trial 2033-12-04
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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