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Last Updated: July 10, 2020

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Patent: 9,822,158

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Summary for Patent: 9,822,158
Title:Method for preparing crystalline insulin
Abstract: A method for crystallizing insulin or insulin analogs under alkaline conditions and purifying the insulin or insulin analog crystals by filtering through a filter and drying the insulin or insulin analog crystals captured on the filter to produce crystalline insulin or insulin analog crystal compositions is described. In particular aspects, the method may be used to crystalize insulin glargine.
Inventor(s): Ortigosa; Allison D. (Harrisonburg, VA), Perry; William (Longmont, CO), Sleevi; Mark C. (Longmont, CO), Sierra; Luis (Dunellen, NJ)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:15/038,495
Patent Claims:see list of patent claims

Details for Patent 9,822,158

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Mylan Pharms Inc SEMGLEE insulin glargine INJECTABLE;INJECTION 210605 001 2020-06-11   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2033-12-04 RX search
Eli Lilly And Co BASAGLAR insulin glargine SOLUTION;SUBCUTANEOUS 205692 001 2016-06-17   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2033-12-04 RX search
Sanofi-aventis U.s. Llc LANTUS insulin glargine INJECTION, SOLUTION 021081 1 2017-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2033-12-04 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Express Scripts

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