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Last Updated: December 1, 2021

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Patent: 9,821,059

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Summary for Patent: 9,821,059
Title:Composition for stabilizing protein and pharmaceutical formulation comprising the same
Abstract: The present invention relates to a composition for stabilizing TNF.alpha.-binding protein exhibiting physiological activity, and more specifically, to a composition for stabilizing protein including basic amino acid and sugar and/or ammonium salt, a pharmaceutical formulation including the same, and a method for stabilizing TNF.alpha.-binding protein. The formulation including basic amino acid; and sugar and/or ammonium salt according to the present invention effectively inhibits aggregation, denaturation and oxidation of TNF.alpha.-binding protein used for treating various diseases, for example, an anti-TNF-alpha antibody, such that the protein is capable of being preserved and stored for a long time, which is widely usable and effective in a medical field using TNF.alpha.-binding protein, for example, an anti-TNF-alpha antibody.
Inventor(s): Park; Soon Jae (Daejeon, KR), Chung; Hye-Shin (Daejeon, KR), Kim; Jin Hwan (Daejeon, KR), Byun; Minsoo (Daejeon, KR), Yeon; Ji Hyeon (Daejeon, KR)
Assignee: ALTEOGEN INC. (Daejeon, KR)
Application Number:14/884,312
Patent Claims:see list of patent claims

Details for Patent 9,821,059

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 2002-12-31 ⤷  Try it Free 2034-10-17
Abbvie Inc. HUMIRA adalimumab Injection 125057 2008-02-21 ⤷  Try it Free 2034-10-17
Abbvie Inc. HUMIRA adalimumab Injection 125057 2013-04-24 ⤷  Try it Free 2034-10-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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