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Last Updated: September 21, 2020

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Patent: 9,821,057

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Summary for Patent: 9,821,057
Title:Anti-IL-6 antibody for use in the treatment of cachexia
Abstract: The present invention is directed to therapeutic methods and compositions, especially subcutaneous and intravenous composition using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments, the anti-IL-6 antibodies will be humanized and/or will be aglycosylated. Also, in preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient\'s survivability or quality of life will preferably be improved.
Inventor(s): Smith; Jeffrey T. L. (Bellevue, WA), Latham; John A. (Seattle, WA), Litton; Mark (Seattle, WA), Schatzman; Randall (Redmond, WA)
Assignee: ALDERBIO HOLDINGS LLC (Las Vegas, NV)
Application Number:14/672,543
Patent Claims:see list of patent claims

Details for Patent 9,821,057

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Novartis ARZERRA ofatumumab INJECTABLE; INJECTION 125326 001 2009-10-26   Start Trial ALDERBIO HOLDINGS LLC (Las Vegas, NV) 2029-11-24 RX search
Novartis KESIMPTA ofatumumab SOLUTION;SUBCUTANEOUS 125326 002 2009-10-26   Start Trial ALDERBIO HOLDINGS LLC (Las Vegas, NV) 2029-11-24 RX search
Genentech PERJETA pertuzumab VIAL; SINGLE-USE 125409 001 2012-06-08   Start Trial ALDERBIO HOLDINGS LLC (Las Vegas, NV) 2029-11-24 RX search
Genentech Inc OCREVUS ocrelizumab INJECTABLE;INJECTION 761053 001 2017-03-28   Start Trial ALDERBIO HOLDINGS LLC (Las Vegas, NV) 2029-11-24 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Harvard Business School
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Colorcon

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