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Last Updated: May 29, 2023

Patent: 9,814,714


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Summary for Patent: 9,814,714
Title:Kinase modulation, and indications therefor
Abstract: The present disclosure provides methods of treating a subject suffering from or at risk of a BRAF V600 mutation or BRAF fusion mutation related disease or condition, without activating the MAPK pathway or inducing expression of MAPK pathway genes in cells harboring wild-type BRAF.
Inventor(s): Ibrahim; Prabha N. (Mountain View, CA), Zhang; Chao (Moraga, CA), Spevak; Wayne (Berkeley, CA), Zhang; Jiazhong (Foster City, CA), Wu; Guoxian (Palo Alto, CA), Lin; Jack (Hercules, CA), Cho; Hanna (Oakland, CA), Nespi; Marika (Berkeley, CA), Shi; Songyuan (Fremont, CA), Ewing; Todd (Walnut Creek, CA), Zhang; Ying (Fremont, CA), Bollag; Gideon (Orinda, CA)
Assignee: Plexxikon Inc. (Berkeley, CA)
Application Number:15/160,729
Patent Claims:see list of patent claims

Details for Patent 9,814,714

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 01/10/1978 ⤷  Try a Trial 2035-05-22
Genentech, Inc. RITUXAN rituximab Injection 103705 11/26/1997 ⤷  Try a Trial 2035-05-22
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 09/25/1998 ⤷  Try a Trial 2035-05-22
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 02/10/2017 ⤷  Try a Trial 2035-05-22
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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