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Generated: September 23, 2019

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Patent: 9,814,714

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Summary for Patent: 9,814,714
Title:Kinase modulation, and indications therefor
Abstract: The present disclosure provides methods of treating a subject suffering from or at risk of a BRAF V600 mutation or BRAF fusion mutation related disease or condition, without activating the MAPK pathway or inducing expression of MAPK pathway genes in cells harboring wild-type BRAF.
Inventor(s): Ibrahim; Prabha N. (Mountain View, CA), Zhang; Chao (Moraga, CA), Spevak; Wayne (Berkeley, CA), Zhang; Jiazhong (Foster City, CA), Wu; Guoxian (Palo Alto, CA), Lin; Jack (Hercules, CA), Cho; Hanna (Oakland, CA), Nespi; Marika (Berkeley, CA), Shi; Songyuan (Fremont, CA), Ewing; Todd (Walnut Creek, CA), Zhang; Ying (Fremont, CA), Bollag; Gideon (Orinda, CA)
Assignee: Plexxikon Inc. (Berkeley, CA)
Application Number:15/160,729
Patent Claims:see list of patent claims

Details for Patent 9,814,714

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX search
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07 ➤ Sign Up Plexxikon Inc. (Berkeley, CA) 2035-05-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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