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Last Updated: December 1, 2021

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Patent: 9,810,692

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Summary for Patent: 9,810,692
Title:Methods for predicting the sensitivity of a subject to immunotherapy
Abstract: The present invention relates to a method of assessing, predicting or monitoring the sensitivity of a subject having a tumor or cancer to an immunotherapeutic molecule acting on the subject\'s T cells, to a method of selecting an appropriate treatment of cancer, to a method of screening or identifying a compound suitable for improving the treatment of a cancer, and to the use of corresponding kits. The method of predicting or monitoring the sensitivity of a subject having a tumor to an immunotherapeutic molecule acting on the subject\'s T cells typically comprises a step a) of determining, in a biological sample from said subject, the expression level of soluble CD25 (sCD25) and, when the expression level is determined, a step b) of comparing at least said expression level to a reference expression level, thereby assessing whether the subject having a tumor is responsive or resistant to the immunotherapeutic molecule.
Inventor(s): Hannani; Dalil (Villejuif, FR), Zitvogel; Laurence (Paris, FR), Robert; Caroline (Fontenay-aux-Roses, FR), Chaput-Gras; Nathalie (Paris, FR)
Application Number:14/438,275
Patent Claims:see list of patent claims

Details for Patent 9,810,692

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bristol-myers Squibb Company YERVOY ipilimumab Injection 125377 2011-03-25 ⤷  Try it Free 2032-10-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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