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Last Updated: December 7, 2021

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Patent: 9,808,528

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Summary for Patent: 9,808,528
Title:Protein-polymer-drug conjugates and methods of using same
Abstract: A polymeric scaffold useful for conjugating with a protein based recognition-molecule (PBRM) to form a PBRM-polymer-drug conjugate is described herein. The scaffold includes one or more terminal maleimido groups. Also disclosed is a PBRM-polymer-drug conjugate prepared from the scaffold. Compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders, such as cancer in a subject having low HER2 expression with the conjugates or their compositions are also described.
Inventor(s): Bodyak; Natalya D. (Brookline, MA), Lowinger; Timothy B. (Carlisle, MA), Park; Peter U. (Somerville, MA), Yurkovetskiy; Aleksandr V. (Littleton, MA)
Assignee: Mersana Therapeutics, Inc. (Cambridge, MA)
Application Number:14/742,936
Patent Claims:see list of patent claims

Details for Patent 9,808,528

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 1998-09-25 ⤷  Try it Free 2034-06-18
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 2017-02-10 ⤷  Try it Free 2034-06-18
Genentech, Inc. PERJETA pertuzumab Injection 125409 2012-06-08 ⤷  Try it Free 2034-06-18
Genentech, Inc. KADCYLA ado-trastuzumab emtansine For Injection 125427 2013-02-22 ⤷  Try it Free 2034-06-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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