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Last Updated: July 3, 2020

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Patent: 9,808,445

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Summary for Patent: 9,808,445
Title:Factor IXa inhibitors
Abstract: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes. ##STR00001##
Inventor(s): Sakurada; Isao (Gotemba, JP), Hirabayashi; Tomokazu (Gotemba, JP), Maeda; Yoshitaka (Gotemba, JP), Nagasue; Hiroshi (Gotemba, JP), Mizuno; Takashi (Gotemba, JP), Xu; Jiayi (Marlboro, NJ), Zhang; Ting (Princeton Junction, NJ), Smith; Cameron (Montgomery Village, MD), Parker; Dann (Cranford, NJ)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:15/303,322
Patent Claims:see list of patent claims

Details for Patent 9,808,445

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech TNKASE tenecteplase VIAL 103909 001 2000-06-02   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP) 2034-04-16 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP) 2034-04-16 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP) 2034-04-16 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP) 2034-04-16 DISCN search
Bayer Hlthcare TRASYLOL aprotinin INJECTABLE;INJECTION 020304 001 1994-02-07   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceutical Co., Ltd. (Tokyo, JP) 2034-04-16 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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