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Generated: August 25, 2019

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Patent: 9,784,748

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Summary for Patent: 9,784,748
Title:Methods for determining anti-drug antibody isotypes
Abstract: The present invention provides assay methods for the determination of one or more anti-drug antibody (ADA) isotypes in a sample. As a non-limiting example, the assays of the present invention are particularly useful for determining different ADA isotypes in samples from ADA-positive patients receiving an anti-TNF.alpha. drug such as REMICADE.TM. (infliximab) or HUMIRA.TM. (adalimumab). The present invention also provides methods for optimizing therapy and/or reducing toxicity in subjects receiving TNF.alpha. inhibitors for the treatment of TNF.alpha.-mediated disease or disorders.
Inventor(s): Wang; Shui Long (San Diego, CA), Ohrmund; Linda (San Diego, CA), Hauenstein; Scott (San Diego, CA), Singh; Sharat (Rancho Santa Fe, CA)
Assignee: NESTEC S.A. (Vevey, CH)
Application Number:13/865,139
Patent Claims:see list of patent claims

Details for Patent 9,784,748

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Ucb Inc CIMZIA certolizumab pegol INJECTABLE; INJECTION 125160 001 2008-04-22   Try a Free Trial NESTEC S.A. (Vevey, CH) 2030-10-18 RX search
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Try a Free Trial NESTEC S.A. (Vevey, CH) 2030-10-18 RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Try a Free Trial NESTEC S.A. (Vevey, CH) 2030-10-18 RX search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Try a Free Trial NESTEC S.A. (Vevey, CH) 2030-10-18 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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