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Last Updated: October 29, 2020

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Patent: 9,770,349

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Summary for Patent: 9,770,349
Title:Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
Abstract: The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.
Inventor(s): Owens; Gary (Earlysville, VA), Lye; Whye-Kei (Charlottesville, VA), Reed; Michael (Charlottesville, VA), Spradlin; Joshua (Charlottesville, VA), Wamhoff; Brian (Charlottesville, VA), Hudson; Matthew (Charlottesville, VA), Looi; Kareen (Charlottesville, VA)
Assignee: University of Virginia Patent Foundation (Charlottesville, VA)
Application Number:11/753,134
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,770,349
Patent Claims:see list of patent claims

Details for Patent 9,770,349

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Ekr Therap RETAVASE reteplase VIAL 103786 001 1998-05-06   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,770,349

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