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Last Updated: November 21, 2019

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Patent: 9,770,349

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Summary for Patent: 9,770,349
Title:Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
Abstract: The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.
Inventor(s): Owens; Gary (Earlysville, VA), Lye; Whye-Kei (Charlottesville, VA), Reed; Michael (Charlottesville, VA), Spradlin; Joshua (Charlottesville, VA), Wamhoff; Brian (Charlottesville, VA), Hudson; Matthew (Charlottesville, VA), Looi; Kareen (Charlottesville, VA)
Assignee: University of Virginia Patent Foundation (Charlottesville, VA)
Application Number:11/753,134
Patent Claims:see list of patent claims

Details for Patent 9,770,349

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial University of Virginia Patent Foundation (Charlottesville, VA) 2022-11-13 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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