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Last Updated: December 3, 2021

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Patent: 9,765,150

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Summary for Patent: 9,765,150
Title:Antibody polypeptides that antagonize CD40L
Abstract: Antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The antibody polypeptides are useful in the treatment of diseases involving CD40L activation, such as graft-related diseases and autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single V.sub.H or V.sub.K domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA) or another antigen.
Inventor(s): Nadler; Steven G. (Princeton, NJ), Tamura; James K. (Yardley, PA), Price; Laura (Langhorne, PA), Rehfuss; Robert P. (North Wales, PA), Suchard; Suzanne J. (Wilmington, DE), Suri; Anish (Yardley, PA), Bryson; James William (Langhorne, PA), Yamniuk; Aaron (Lawrenceville, NJ), Grant; Steven (Swaffham Prior, GB), Ignatovich; Olga (Cambridge, GB), Drew; Philip (Histon, GB)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ) Domantis Limited (Brentford, Middlesex, GB)
Application Number:14/950,949
Patent Claims:see list of patent claims

Details for Patent 9,765,150

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bristol-myers Squibb Company NULOJIX belatacept For Injection 125288 2011-06-15 ⤷  Try it Free 2031-10-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson

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