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Last Updated: January 26, 2021

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Patent: 9,745,577

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Summary for Patent: 9,745,577

Title:	Reducing intron retention
Abstract:	Disclosed herein are methods, compositions, polynucleic acid polymers, assays, and kits for inducing processing of a partially processed mRNA transcript to remove a retained intron to produce a fully processed mRNA transcript that encodes a full-length functional form of a protein. Also described herein are methods and compositions for treating a disease or condition characterized by impaired production of a full-length functional form of a protein or for treating a disease or condition characterized by a defective splicing in a subject.
Inventor(s):	Vorechovsky; Igor (Southampton, GB), Kralovicova; Jana (Southampton, GB)
Assignee:	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)
Application Number:	14/741,071
Patent Claims:	see list of patent claims

Details for Patent 9,745,577

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Schering	INTRON A	interferon alfa-2b	VIAL	103132	003	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	002	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	001	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 9,745,577

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2015193651	Start Trial
United States of America	10538764	Start Trial
United States of America	2016017322	Start Trial
>Country	>Patent Number	>Estimated Expiration

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