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Last Updated: February 18, 2020

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Patent: 9,745,577

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Summary for Patent: 9,745,577

Title:	Reducing intron retention
Abstract:	Disclosed herein are methods, compositions, polynucleic acid polymers, assays, and kits for inducing processing of a partially processed mRNA transcript to remove a retained intron to produce a fully processed mRNA transcript that encodes a full-length functional form of a protein. Also described herein are methods and compositions for treating a disease or condition characterized by impaired production of a full-length functional form of a protein or for treating a disease or condition characterized by a defective splicing in a subject.
Inventor(s):	Vorechovsky; Igor (Southampton, GB), Kralovicova; Jana (Southampton, GB)
Assignee:	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)
Application Number:	14/741,071
Patent Claims:	see list of patent claims

Details for Patent 9,745,577

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Schering	INTRON A	interferon alfa-2b	VIAL	103132	001	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	002	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	003	1986-06-04	Start Trial	UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB)	2034-06-16	RX		search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 9,745,577

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Country	Patent Number	Publication Date
Australia	2015275870	Feb 02, 2017
Canada	2951208	Dec 23, 2015
China	107073137	Aug 18, 2017
European Patent Office	3155124	Apr 19, 2017
United Kingdom	201410693	Jul 30, 2014
Japan	2017519766	Jul 20, 2017
South Korea	20170029512	Mar 15, 2017
>Country	>Patent Number	>Publication Date

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