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Patent: 9,745,577
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Summary for Patent: 9,745,577
Title: | Reducing intron retention |
Abstract: | Disclosed herein are methods, compositions, polynucleic acid polymers, assays, and kits for inducing processing of a partially processed mRNA transcript to remove a retained intron to produce a fully processed mRNA transcript that encodes a full-length functional form of a protein. Also described herein are methods and compositions for treating a disease or condition characterized by impaired production of a full-length functional form of a protein or for treating a disease or condition characterized by a defective splicing in a subject. |
Inventor(s): | Vorechovsky; Igor (Southampton, GB), Kralovicova; Jana (Southampton, GB) |
Assignee: | UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB) |
Application Number: | 14/741,071 |
Patent Claims: | see list of patent claims |
Details for Patent 9,745,577
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 003 | 1986-06-04 | Start Trial | UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB) | 2034-06-16 | RX | search | |
Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 002 | 1986-06-04 | Start Trial | UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB) | 2034-06-16 | RX | search | |
Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 001 | 1986-06-04 | Start Trial | UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB) | 2034-06-16 | RX | search | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 9,745,577
Country | Patent Number | Estimated Expiration |
---|---|---|
World Intellectual Property Organization (WIPO) | 2015193651 | Start Trial |
United States of America | 10538764 | Start Trial |
United States of America | 2016017322 | Start Trial |
>Country | >Patent Number | >Estimated Expiration |