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Last Updated: September 22, 2020

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Patent: 9,732,343

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Summary for Patent: 9,732,343
Title:Composition and method for inner ear sensory hair cell regeneration and replacement
Abstract: A composition and method for replacement and regeneration of hair cells of the inner ear is provided. The composition comprises an active agent in an amount effective to decrease Hes1 gene expression in a tissue of the inner ear. The active agent can be short interfering RNA (siRNA) molecules encapsulated in a biodegradable nanoparticle. The method involves administering a solution to the inner ear where the solution contains an active agent in an amount effective to decrease Hes1 gene expression.
Inventor(s): Kopke; Richard D. (Oklahoma City, OK)
Assignee: HOUGH EAR INSTITUTE (Oklahoma City, OK)
Application Number:14/803,737
Patent Claims:see list of patent claims

Details for Patent 9,732,343

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial HOUGH EAR INSTITUTE (Oklahoma City, OK) 2030-06-04 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial HOUGH EAR INSTITUTE (Oklahoma City, OK) 2030-06-04 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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