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Last Updated: December 8, 2021

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Patent: 9,725,716

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Summary for Patent: 9,725,716
Title:Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
Abstract: Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.
Inventor(s): Burghes; Arthur (Columbus, OH), Porensky; Paul (Worthington, OH), Kaspar; Brian (New Albany, OH)
Assignee: Ohio State Innovation Foundation and Research Institute at Nationwide Children\'s Hospital (Columbus, OH)
Application Number:14/363,670
Patent Claims:see list of patent claims

Details for Patent 9,725,716

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2031-12-06
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2031-12-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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