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Last Updated: December 11, 2019

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Patent: 9,701,963

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Summary for Patent: 9,701,963
Title:Complement component C5 iRNA compositions and methods of use thereof
Abstract: The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria.
Inventor(s): Fitzgerald; Kevin (Brookline, MA), Butler; James (Lynnfield, MA), Bettencourt; Brian (Groton, MA), Borodovsky; Anna (Melrose, MA), Kuchimanchi; Satyanarayana (Acton, MA), Charisse; Klaus (Acton, MA), Manoharan; Muthiah (Weston, MA), Maier; Martin (Belmont, MA), Rajeev; Kallanthottathil G. (Wayland, MA), Foster; Donald (Attleboro, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:15/151,568
Patent Claims:see list of patent claims

Details for Patent 9,701,963

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Alexion Pharm SOLIRIS eculizumab INJECTABLE; IV (INFUSION) 125166 001 2007-03-16   Start Trial Alnylam Pharmaceuticals, Inc. (Cambridge, MA) 2033-03-14 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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