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Last Updated: March 26, 2023

Patent: 9,688,752


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Summary for Patent: 9,688,752
Title:Low acidic species compositions and methods for producing and using the same using displacement chromatography
Abstract: The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided.
Inventor(s): Wang; Chen (Shrewsbury, MA), Coppola; Germano (Shrewsbury, MA), Chumsae; Chris (North Andover, MA)
Assignee: AbbVie Inc. (North Chicago, IL)
Application Number:14/635,505
Patent Claims:see list of patent claims

Details for Patent 9,688,752

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 12/31/2002 See Plans and Pricing 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 02/21/2008 See Plans and Pricing 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 04/24/2013 See Plans and Pricing 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 09/23/2014 See Plans and Pricing 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 11/23/2015 See Plans and Pricing 2033-10-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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