Patent: 9,688,752
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Summary for Patent: 9,688,752
Title: | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
Abstract: | The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided. |
Inventor(s): | Wang; Chen (Shrewsbury, MA), Coppola; Germano (Shrewsbury, MA), Chumsae; Chris (North Andover, MA) |
Assignee: | AbbVie Inc. (North Chicago, IL) |
Application Number: | 14/635,505 |
Patent Claims: | see list of patent claims |
Details for Patent 9,688,752
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 12/31/2002 | See Plans and Pricing | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 02/21/2008 | See Plans and Pricing | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 04/24/2013 | See Plans and Pricing | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 09/23/2014 | See Plans and Pricing | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 11/23/2015 | See Plans and Pricing | 2033-10-18 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |