The present invention relates to a membrane comprising at least one positively charged, synthetic, hydrophobic polymer, at least one hydrophilic polymer and at least one plasticizer; wherein said membrane is flexible and is capable of supporting at least one of cell adherence, cell proliferation or cell differentiation. The invention further relates to use of a membrane of the invention in the preparation of an implantable devices including cell delivery systems, cell growing surfaces and scaffolds. The invention further provides methods for promoting tissue regeneration in a defected tissue region applying membranes of the invention.
Friedman; Michael (Jerusalem, IL), Sasson; Yoel (Rehovot, IL), Grin; Ada (Rehovot, IL), Mosheiff; Rami (Jerusalem, IL), Rachmilewitz; Jacob (Modi\'in, IL)
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (Jerusalem, IL) HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. (Jerusalem, IL)
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